Ruxandra's Substack

A manifesto for reviving biopharma productivity

When it comes to Eroom's Law, some of the most important problems are the boring ones

Dec 10 • Ruxandra Teslo

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Of course motherhood drives the gender wage gap

Discussions around the motherhood wage gap reveal the limits of autism and the benefits of female intuition

Dec 6 • Ruxandra Teslo

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November 2025

What will it take for AI to change drug discovery?

Some thoughts on avoiding self delusion.

Nov 9 • Ruxandra Teslo

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September 2025

Affirmative action for anti-inefficiency academics?

A follow-up to my hobbit post

Sep 18 • Ruxandra Teslo

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For clinical trial reform, we need more hobbits

Or how hobbitian courage is important

Sep 18 • Ruxandra Teslo

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Building in the world of flesh needs regulatory transparency

We want more drugs, but we make it the hardest to achieve that

Sep 6 • Ruxandra Teslo

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Some clarifications on Hepatitis B transmissibility

In case people were feeling misled by how transmissible Hep B is, here is a clarification.

Sep 4 • Ruxandra Teslo

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Your newborn is not Hepatitis B vaccinated because of wokeness

Being reflexively anti-system is bad

Sep 1 • Ruxandra Teslo

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August 2025

My ovaries do not have cysts.

On the unaptly called Polycystic Ovary Syndrome

Aug 23 • Ruxandra Teslo

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April 2025

A response to Kate Manne on pregnancy

On the importance of well-reported data

Apr 29 • Ruxandra Teslo

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Spotlight on immune aging

Quick thoughts on some confirmatory studies to my previous post on immune aging and which both came out today.

Apr 23 • Ruxandra Teslo

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Autoimmune therapies: an inspiration for anti-aging therapies?

On how anti-aging therapies could piggyback on autoimmune treatment strategies in the same way the latter piggybacked on advances in cancer therapies

Apr 20 • Ruxandra Teslo

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