Ruxandra's Substack

The Bureaucracy Blocking the Chance at a Cure

How early-stage clinical trials became unnecessarily expensive and inefficient—and how we can fix them, inspired by a recent story about a dog treated…

Mar 15 • Ruxandra Teslo

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The Moral Crisis Behind the Billionaire Wealth Tax

On wealth taxes, tech billionaires, and the moral vacuum of modern elites.

Mar 11 • Ruxandra Teslo

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Equality as a Consolation Prize

In a secular world, equality is a last attempt to offer some dignity to the weak

Mar 3 • Ruxandra Teslo

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February 2026

A response to Dario Amodei on AI & clinical trials

AI won't automatically accelerate clinical trials

Feb 28 • Ruxandra Teslo

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The 30-Year Success Story the US FDA Ignored

And why there is hope this is changing now

Feb 18 • Ruxandra Teslo

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The FDA should not change its mind last minute

In which I discuss the implications of the FDA's latest decision on Moderna's influenza vaccine

Feb 11 • Ruxandra Teslo

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December 2025

A manifesto for reviving biopharma productivity

When it comes to Eroom's Law, some of the most important problems are the boring ones

Dec 10, 2025 • Ruxandra Teslo

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Of course motherhood drives the gender wage gap

Discussions around the motherhood wage gap reveal the limits of autism and the benefits of female intuition

Dec 6, 2025 • Ruxandra Teslo

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November 2025

What will it take for AI to change drug discovery?

Some thoughts on avoiding self delusion.

Nov 9, 2025 • Ruxandra Teslo

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September 2025

For clinical trial reform, we need more hobbits

Or how hobbitian courage is important

Sep 18, 2025 • Ruxandra Teslo

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Some clarifications on Hepatitis B transmissibility

In case people were feeling misled by how transmissible Hep B is, here is a clarification.

Sep 4, 2025 • Ruxandra Teslo

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Your newborn is not Hepatitis B vaccinated because of wokeness

Being reflexively anti-system is bad

Sep 1, 2025 • Ruxandra Teslo

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