Ruxandra's Substack

Manufacturing requirements are killing cell and gene therapy

Some of the most promising drugs are bottlenecked by a "boring" but incredibly important problem

Jun 10 • Ruxandra Teslo

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How China is getting ahead in biotech: a case study

A drug for multiple myeloma should have been an early warning that China is racing ahead in biotech

Jun 7 • Ruxandra Teslo

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The blood cancer that became solvable

Multiple myeloma is brutal. We may finally have a cure, but American regulatory inertia means that it was discovered abroad.

Published on The Works in Progress Newsletter • Jun 6

May 2026

Pancreatic cancer just met its match

A disease that was once a death sentence is increasingly treatable

Published on The Works in Progress Newsletter • May 13

April 2026

Considerations for egg freezing: a practical guide

Some additional notes on practical steps towards egg freezing

Apr 12 • Ruxandra Teslo and Luzia Bruckamp

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March 2026

The Bureaucracy Blocking the Chance at a Cure

How early-stage clinical trials became unnecessarily expensive and inefficient—and how we can fix them, inspired by a recent story about a dog treated…

Mar 15 • Ruxandra Teslo

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The Moral Crisis Behind the Billionaire Wealth Tax

On wealth taxes, tech billionaires, and the moral vacuum of modern elites.

Mar 11 • Ruxandra Teslo

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Equality as a Consolation Prize

In a secular world, equality is a last attempt to offer some dignity to the weak

Mar 3 • Ruxandra Teslo

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February 2026

A response to Dario Amodei on AI & clinical trials

AI won't automatically accelerate clinical trials

Feb 28 • Ruxandra Teslo

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The 30-Year Success Story the US FDA Ignored

And why there is hope this is changing now

Feb 18 • Ruxandra Teslo

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The FDA should not change its mind last minute

In which I discuss the implications of the FDA's latest decision on Moderna's influenza vaccine

Feb 11 • Ruxandra Teslo

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December 2025

A manifesto for reviving biopharma productivity

When it comes to Eroom's Law, some of the most important problems are the boring ones

Dec 10, 2025 • Ruxandra Teslo

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